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Design flow rate and pressure difference (50Pa?)

I'm trying to define in OpenStudio Space Infiltration Design Flow rate, by using a design flow rate parameters of a buildings similar to my study cases. My reference data have the results with 50Pa of pressure difference. I read the engineering reference and don't see any limit to the pressure use for that. (For the case of Effective Leakage area, it is well defined that should be 4Pa) Can i use a flow rate of 50Pa for the simulation? I hope anyone can help me,