Can anyone guide me on how EnergyPlus can be used for parallel processing?

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I believe you are asking about parametric analysis, or using a simulation manager. I'm a design builder user, which has parametric analysis tools as well as a separate program called "simulation manager" that can run simultaneous simulations.

So, yes, you can run simultaneous simulations, but you will need to figure out how to launch them Perhaps: EP-Launch.

I’m not familiar with running parametric analyses in OpenStudio or DesignBuilder, but here’s my approach for parallel processing using multiple CPU cores in a Windows/Linux environment with Python:

1. Parameter Assignment: Write a function to apply specific parameters or inputs to your IDF file. And assign the correct Energy+.idd path. (see the EPPY library for reference).

2. Temporary Workspace: Within that function, create random temporary folders to store copies of your IDF and EPW files for each run (see the tempfile module).

3. Parallel Execution: Implement multiprocessing to run multiple simulations in parallel, leveraging all available CPU cores (see the multiprocessing module).

Note: Be sure to clean up by deleting all temporary folders and files once the simulations have finished. In Windows, the multiprocessing module was previously limited to a maximum of 64 CPU cores. I’m not sure if this limitation still applies.