Question-and-Answer Resource for the Building Energy Modeling Community
 | 1 | initial version |
To run multiple simulations and change the parameters you can try eppy. OpenStudio is another choice but I don't know if they Python bindings are available by default. If you are trying to use Python as part of simulating an EMS system or modifying parameters during the timesteps of an single simulation you might want to look at the Group - Python Plugins/Python EMS in the InputOutputReference.pdf.
