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You should be able to use the Modelica Buildings Library (https://simulationresearch.lbl.gov/modelica/) for this purpose. It has a room model that has been used for dynamic multi-zone heat transfer in buildings with a few zones, but it has no graphical geometry editor, you will need to enter the surface areas and orientation in a text editor (https://simulationresearch.lbl.gov/modelica/releases/latest/help/Buildings_ThermalZones_Detailed_UsersGuide.html). This model has no daylighting simulation, but you could read in a time schedule that you compute with a lighting simulation software. Controls, pressure in duct networks and the resulting flow distribution is computed in Modelica.

If you are willing to setup and try research code on Linux, which is still in active development and debugging, you could directly couple Modelica HVAC and control from the Buildings Library to the EnergyPlus envelop model, see https://lbl-srg.github.io/soep/.