modeling building with large elevation difference from weather data elevation

edit

I am trying to study wind driven natural ventilation for a high rise 22-floor apartment with airflow network. the building is located on site with higher altitude from the weather station data.

• my case : building located on highland region, about 55m from sea level
• weather data : Site:Location Elevation is at 3.7m from sea level
• model description : since floor plans are typical, only the middle portion of the building is modelled (in this case the whole floor plan at 10th floor).

1. in modeling the geometry, should i lift the whole building geometry 55m up from the "origin (0,0,0)" point to account for the elevation difference?
2. what is the best practice on modeling geometry with similar case? since pressure, temperature and wind velocity varies with height as described in detail here

thanks!