Can We Connect One AirLoop with Another AirLoop

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I would like to use EnergyPlus or OpenStudio to model a huge AHU system that supply the cooled air to each floor by using super fans. And each floor also has some terminal boxes that can modulate and heat the cooled air before delivering to the zone. So my idea is as following:

1) Create a central air loop for that huge AHU system 2) Create an extra air loop for each floor that contains the zone and terminal box. 3) Connect each floor's air loop to the central air loop to allow the cooled air to each floor.

Does anyone has the similar experience in connecting two air loops together by some methods? If my ideas can't be true, does anyone has a better idea? Thanks!