how to simulate without thermostat schedule?

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Hello I have created a building and hot water heating system with water radiator. I want to simulate without any thermostats schedule for heating setpoint. The heating system works without any thermostat in spaces. The boiler has supply water thermostat installed but there is not any thermostats in spaces to control temperature.

I am using designbuilder. Let me know if I should use other software to do this.