Question-and-Answer Resource for the Building Energy Modeling Community
 | 1 | initial version |
Since the equations that are solved by AirflowNetwork (and other similar tools) can't represent the gradient phenomenon that are common in large spaces, getting a reasonable solution out of them by subdividing a volume is a pretty chancy business at best. Accordingly, there's not much in the way of best practices, other than perhaps "don't do this". So the answers to your questions are: no, no, and no.
With that said, if you know what the flows should look like it is possible to construct a network that gives plausible results and might match up acceptably to more detailed results (i.e. CFD). But you have to know what the flow will look like, and it won't be a substitute for a CFD simulation.
